Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines-Reference-Cited by-同舟云学术

Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines

Published:1998-08 Issue:8 Volume:39 Page:1722-1727
ISSN:0022-2275
Container-title:Journal of Lipid Research
language:en
Short-container-title:Journal of Lipid Research

Author:

Lee Oneil,Chang Catherine C.Y.,Lee William,Chang Ta-Yuan

Publisher

Elsevier BV

Subject

Cell Biology,Endocrinology,Biochemistry

Reference25 articles.

1. Acyl-coenzyme A:cholesterol acyltransferase;Chang;Annu. Rev. Biochem.,1997

2. ACAT inhibition decreases LDL cholesterol in rabbits fed a cholesterol-free diet: marked changes in LDL cholesterol without changes in LDL receptor mRNA abundance;Krause;Arterioscler. Thromb.,1994

3. Inhibition of hepatic ACAT decreases apoB secretion in miniature pigs fed a cholesterol-free diet;Huff;Arterioscler. Thromb.,1994

4. ACAT inhibitors CL 283,546 and CL 283,796 reduce LDL cholesterol without affecting cholesterol absorption in African green monkeys;Wrenn;J. Lipid Res.,1995

5. Gene expression of acyl-coenzyme A:cholesterol acyltransferase is upregulated in human monocytes during differentiation and foam cell formation;Wang;Arterioscler. Thromb. Vasc. Biol.,1996

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