Phosphodiesterase inhibitors suppress proliferation of peripheral blood mononuclear cells and interleukin-4 and -5 secretion by human T-helper type 2 cells

Author:

Crocker I.Caroline,Townley Robert G.,Khan Manzoor M.

Publisher

Elsevier BV

Subject

Pharmacology

Reference38 articles.

1. Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5);Campbell,1987

2. Increased interleukin-4 production by atopic mononuclear leukocytes correlates with increased cyclic adenosine monophosphate-phosphodiesterase activity and is reversible by phosphodiesterase inhibition;Chan;J. Invest. Dermatol.,1993

3. Differential inhibitor effects on cyclic adenosine monophosphate-phosphodiesterase isoforms in atopic and normal leukocytes;Chan;J. Lab. Clin. Med.,1993

4. Phosphodiesterase inhibition by Ro20-1724 reduces hyper-IgE synthesis by atopic dermatitis cells in vitro;Cooper;J. Invest. Dermatol.,1985

5. CD4 T-lymphocyte activation in acute severe asthma;Corrigan,1990

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