Phosphodiesterase Inhibition by Ro 20-1724 Reduces Hyper-IgE Synthesis by Atopic Dermatitis Cells In Vitro

Author:

Cooper Kevin D.,Kang Kefei,Chan Sai C.,Hanifin Jon M.

Publisher

Elsevier BV

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference30 articles.

1. Skin histamine levels in chronic atopic dermatitis;Johnson;J Invest Dermatol,1960

2. Localization and content of histamine in normal diseased skin;Juhlin;Acta Derm Venereol (Stockh),1967

3. Heterologous desensitization of leukocytes: a possible mechanism of beta adrenergic blockade in atopic dermatitis;Safka;J Allergy Clin Immunol,1981

4. Functional desensitization due to stimulation of cyclic AMP-phosphodiesterase in human mononuclear leukocytes;Chan;J Cyclic Nucleotide Res,1982

5. Elevated leukocyte cyclic AMP-phosphodiesterase in atopic disease: a possible mechanism for cyclic AMP-agonist hyporesponsiveness;Grewe;J Allergy Clin Immunol,1982

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