Increased Interleukin-4 Production by Atopic Mononuclear Leukocytes Correlates with Increased Cyclic Adenosine Monophosphate – Phosphodiesterase Activity and Is Reversible by Phosphodiesterase Inhibition
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Dermatology,Molecular Biology,Biochemistry
Reference19 articles.
1. Immunopharmacology of the atopic diseases;Hanifin;J Invest Dermatol,1985
2. Heterologous desensitization of leukocytes: a possible mechanism of beta adrenergic blockade in atopic dermatitis;Safko;J Allergy Clin Immunol,1981
3. Elevated leukocyte cyclic AMP-phosphodiesterase in atopic disease: a possible mechanism for cyclic AMP-agonist hyporesponsiveness;Grewe;J Allergy Clin Immunol,1982
4. Phosphodiesterase inhibition by Ro 20-1724 reduces hyper-IgE synthesis by atopic dermatitis cells in vitro;Cooper;J Invest Dermatol,1985
5. IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons γ and α and prostaglandin E2;Pene;Proc Natl Acad Sci USA,1988
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