Discovery of novel sulfonamides as potent and selective inhibitors against human and mouse 11β-hydroxysteroid dehydrogenase type 1
Author:
Publisher
Elsevier BV
Subject
Endocrinology,Molecular Biology,Biochemistry
Reference20 articles.
1. Demonstration of proof of mechanism and pharmacokinetics and pharmacodynamic relationship with 4′-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide (PF-915275), an inhibitor of 11β-hydroxysteroid dehydrogenase type 1, in cynomolgus monkeys;Bhat;J. Pharmacol. Exp. Ther.,2008
2. Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy;Friesner;J. Med. Chem.,2004
3. 11Beta-hydroxysteroid dehydrogenase type 1 inhibitors as promising therapeutic drugs for diabetes: status and development;Ge;Curr. Med. Chem.,2010
4. Development of 11beta-HSD1 inhibitors for the treatment of type 2 diabetes;Hale;Mini Rev. Med. Chem.,2008
5. The metabolic syndrome and cardiovascular risk;Hu;Curr. Diabetes Rev.,2005
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2. Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors;Bioorganic & Medicinal Chemistry;2015-12
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