Demonstration of Proof of Mechanism and Pharmacokinetics and Pharmacodynamic Relationship with 4′-Cyano-biphenyl-4-sulfonic Acid (6-Amino-pyridin-2-yl)-amide (PF-915275), an Inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1, in Cynomolgus Monkeys-Reference-Cited by-同舟云学术

Demonstration of Proof of Mechanism and Pharmacokinetics and Pharmacodynamic Relationship with 4′-Cyano-biphenyl-4-sulfonic Acid (6-Amino-pyridin-2-yl)-amide (PF-915275), an Inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1, in Cynomolgus Monkeys

Published:2007-10-05 Issue:1 Volume:324 Page:299-305
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Bhat B. Ganesh,Hosea Natilie,Fanjul Andrea,Herrera Jocelyn,Chapman Justin,Thalacker Fred,Stewart Paul M.,Rejto Paul A.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference23 articles.

1. Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Improves Hepatic Insulin Sensitivity in Hyperglycemic Mice Strains

2. Splanchnic Cortisol Production Occurs in Humans

3. Classic and Recent Etiologies of Cushing??s Syndrome

4. Human 11β-hydroxysteroid dehydrogenase: Studies on the stably transfected isoforms and localization of the type 2 isozyme within renal tissue

Cited by 57 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of a human blood biomarker of pharmacological 11β‐hydroxysteroid dehydrogenase 1 inhibition;British Journal of Pharmacology;2023-10-19

2. Tumors produce glucocorticoids by metabolite recycling, not synthesis, and activate Tregs to promote growth;Journal of Clinical Investigation;2023-09-15

3. 11β-Hydroxysteroid Dehydrogenase Type 1 as a Potential Treatment Target in Cardiovascular Diseases;Journal of Clinical Medicine;2022-10-20

4. Association between Selected Polymorphisms rs12086634, rs846910, rs4844880, rs3753519 of 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) and the Presence of Insulin Resistance in the Polish Population of People Living in Upper Silesia;International Journal of Environmental Research and Public Health;2021-09-27

5. The Stress Axis in Obesity and Diabetes Mellitus: An Update;Endocrines;2021-09-06