Discovery of potential ZAP-70 kinase inhibitors: Pharmacophore design, database screening and docking studies
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference22 articles.
1. Defective T cell receptor signaling and CD8+ thymic selection in humans lacking Zap-70 kinase
2. Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes.
3. F2 (Pmp)2 -TAM ζ3 , a Novel Competitive Inhibitor of the Binding of ZAP-70 to the T Cell Antigen Receptor, Blocks Early T Cell Signaling
4. ZAP-70 Deficiency in an Autosomal Recessive form of Severe Combined Immunodeficiency
5. Human Severe Combined Immunodeficiency Due to a Defect in ZAP-70, a T Cell Tyrosine Kinase
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