Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
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1. Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis;Journal of Medicinal Chemistry;2023-08-18
2. Mechanistic insights into the allosteric inactivation mechanism of ZAP-70 induced by the hot spot W165C mutation;Journal of Biomolecular Structure and Dynamics;2023-07-28
3. Pharmacological strategies for mitigating anti-TNF biologic immunogenicity in rheumatoid arthritis patients;Current Opinion in Pharmacology;2023-02
4. SYK and ZAP70 kinases in autoimmunity and lymphoid malignancies;Cellular Signalling;2022-06
5. Expanding the Diversity at the C-4 Position of Pyrido[2,3-d]pyrimidin-7(8H)-ones to Achieve Biological Activity against ZAP-70;Pharmaceuticals;2021-12-15
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