Structure-based drug design of an inhibitor of the SARS-CoV-2 (COVID-19) main protease using free software: A tutorial for students and scientists

Author:

Zhang ShengORCID,Krumberger MajORCID,Morris Michael A.ORCID,Parrocha Chelsea Marie T.ORCID,Kreutzer Adam G.ORCID,Nowick James S.ORCID

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference24 articles.

1. Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease;Dai;Science,2020

2. Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease;Douangamath;Nat. Commun.,2020

3. Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication;Vuong;Nat. Commun.,2020

4. α-Ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication: structure-based design, synthesis, and activity assessment;Zhang;J. Med. Chem.,2020

5. Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors;Jin;Nature,2020

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