α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment-Reference-Cited by-全球学者库

α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment

Published:2020-02-11 Issue:9 Volume:63 Page:4562-4578
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Linlin¹²,Lin Daizong¹²³,Kusov Yuri¹,Nian Yong³,Ma Qingjun¹,Wang Jiang³,von Brunn Albrecht⁴,Leyssen Pieter⁵,Lanko Kristina⁵,Neyts Johan⁵,de Wilde Adriaan⁶,Snijder Eric J.⁶,Liu Hong³^ORCID,Hilgenfeld Rolf¹²³^ORCID

Affiliation:

1. Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lübeck, 23562 Lübeck, Germany

2. German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems Site, University of Lübeck, 23562 Lübeck, Germany

3. Shanghai Institute of Materia Medica, 201203 Shanghai, China

4. Max von Pettenkofer Institute, Ludwig-Maximilians-University Munich, 80336 Munich, Germany

5. Rega Institute for Medical Research, University of Leuven, 3000 Leuven, Belgium

6. Leiden University Medical Center, 2333 ZA Leiden, The Netherlands

Funder

Bundesministerium f?r Bildung und Forschung

Directorate-General for Research and Innovation

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01828

Reference65 articles.

1. From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses

2. Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

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