Design and synthesis of copper(<scp>ii</scp>) and nickel(<scp>ii</scp>) complexes as potential inhibitors against SARS-CoV-2 viral RNA binding protein and Omicron RBD protein-Reference-Cited by-同舟云学术

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Design and synthesis of copper(ii) and nickel(ii) complexes as potential inhibitors against SARS-CoV-2 viral RNA binding protein and Omicron RBD protein

Published:2024 Issue:34 Volume:48 Page:15053-15076
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Ahmad Reyaz¹^ORCID,Choudhary Mukesh¹^ORCID

Affiliation:

1. Department of Chemistry, National Institute of Technology Patna, Patna, 800005 Bihar, India

Abstract

Two bis-Schiff base metal(ii) complexes [Cu(L)2](1) and [Ni(L)2](2) were designed and synthesized as potential inhibitors for the development of new anti-SARS-CoV-2 Omicron and anti-HIV drugs.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D4NJ02753A

Reference108 articles.

1. Site-specific recognition of SARS-CoV-2 nsp1 protein with a tailored titanium dioxide nanoparticle – elucidation of the complex structure using NMR data and theoretical calculation

2. The SARS-CoV-2 RNA–protein interactome in infected human cells

3. The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

4. Defining Distinct RNA-Protein Interactomes of SARS-CoV-2 Genomic and Subgenomic RNAs

5. Multiple Roles of SARS-CoV-2 N Protein Facilitated by Proteoform-Specific Interactions with RNA, Host Proteins, and Convalescent Antibodies

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