Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment

Published:2021-08 Issue: Volume:220 Page:113437
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Lei Yu,Zhang Bing,Zhang Yan,Dai Xiwen,Duan Yulin,Mao Qing,Gao Jun,Yang Yuwei,Bao Ziyang,Fu Xuefeng,Ping Kunqi,Yan Chengda,Mou Yanhua,Wang Shaojie

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference48 articles.

1. Factor XIa inhibitors as new anticoagulants;Quan;J. Med. Chem.,2018

2. Phenylimidazoles as potent and selective inhibitors of coagulation factor XIa with in vivo antithrombotic activity;Hangeland;J. Med. Chem.,2014

3. Inhibition of factor XI activity as a promising antithrombotic strategy;Chen;Drug Discov. Today,2014

4. Discovery of a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species;Yang;J. Med. Chem.,2020

5. Factor XIa inhibitors: a review of the patent literature;Al-Horani;Expert Opin. Ther. Pat.,2016

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Future of factor XI inhibitors in cardiovascular practice;Minerva Cardiology and Angiology;2024-05

2. Alkylation of Ethyl 2-Aryl-1-hydroxy-4-methyl-1H-imidazole-5-carboxylates with Benzyl Halides;Russian Journal of Organic Chemistry;2024-02

3. 2-Aryl-1-hydroxyimidazoles possessing antiviral activity against a wide range of orthopoxviruses, including the variola virus;RSC Medicinal Chemistry;2024

4. Factor XIa Inhibitors in Anticoagulation Therapy: Recent Advances and Perspectives;Journal of Medicinal Chemistry;2023-04-10

5. Toward the Development of a Manufacturing Process for Milvexian: Scale-Up Synthesis of the Side Chain;Organic Process Research & Development;2023-04-03

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3