Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy-Reference-Cited by-同舟云学术

Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy

Published:2021-08 Issue: Volume:220 Page:113431
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Vuorinen Aini^ORCID,Wilkinson Isabel V.L.^ORCID,Chatzopoulou Maria,Edwards Ben,Squire Sarah E.,Fairclough Rebecca J.,Bazan Noelia Araujo^ORCID,Milner Josh A.,Conole Daniel^ORCID,Donald James R.^ORCID,Shah Nandini,Willis Nicky J.^ORCID,Martínez R. Fernando^ORCID,Wilson Francis X.^ORCID,Wynne Graham M.,Davies Stephen G.,Davies Kay E.,Russell Angela J.^ORCID

Funder

EPSRC

Medical Research Council

Muscular Dystrophy Association

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference29 articles.

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2. The potential of utrophin modulators for the treatment of Duchenne muscular dystrophy;Guiraud;Expert Opin. Orphan Drugs.,2018

3. Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of duchenne muscular dystrophy;Chancellor;J. Med. Chem.,2011