Discovery of 2-Arylbenzoxazoles as Upregulators of Utrophin Production for the Treatment of Duchenne Muscular Dystrophy-Reference-Cited by-同舟云学术

Discovery of 2-Arylbenzoxazoles as Upregulators of Utrophin Production for the Treatment of Duchenne Muscular Dystrophy

Published:2011-04-15 Issue:9 Volume:54 Page:3241-3250
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chancellor Daniel R.¹,Davies Kay E.²,De Moor Olivier¹,Dorgan Colin R.¹,Johnson Peter D.¹,Lambert Adam G.¹,Lawrence Daniel¹,Lecci Cristina¹,Maillol Carole¹,Middleton Penny J.¹,Nugent Gary¹,Poignant Séverine D.¹,Potter Allyson C.²,Price Paul D.¹,Pye Richard J.¹,Storer Richard¹,Tinsley Jonathon M.¹,van Well Renate¹,Vickers Richard¹,Vile Julia¹,Wilkes Fraser J.¹,Wilson Francis X.¹,Wren Stephen P.¹,Wynne Graham M.¹

Affiliation:

1. Summit plc, 91 Milton Park, Abingdon, Oxfordshire, OX14 4RY, United Kingdom

2. Department of Physiology, Anatomy and Genetics, University of Oxford, Le Gros Clark Building, South Parks Road, Oxford, OX1 3QX, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200135z

Reference28 articles.

1. Duchenne muscular dystrophy and dystrophin: pathogenesis and opportunities for treatment

2. New therapies for Duchenne muscular dystrophy: challenges, prospects and clinical trials