Improving selectivity preserving affinity: New piperidine-4-carboxamide derivatives as effective sigma-1-ligands
Author:
Funder
(Research Fund University of Trieste-Italy
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference58 articles.
1. Phencyclidine and σ opiate receptors in brain: Biochemical and autoradiographical differentiation
2. A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain
3. Regulation of σ receptors and responsiveness to guanine nucleotides following repeated exposure of rats to haloperidol: further evidence for multiple σ binding sites
4. A proposal for the classification of sigma binding sites
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