Design, synthesis and evaluation of dialkyl 4-(benzo[d][1,3]dioxol-6-yl)-1,4-dihydro-2,6-dimethyl-1-substituted pyridine-3,5-dicarboxylates as potential anticonvulsants and their molecular properties prediction-Reference-Cited by-同舟云学术

Design, synthesis and evaluation of dialkyl 4-(benzo[d][1,3]dioxol-6-yl)-1,4-dihydro-2,6-dimethyl-1-substituted pyridine-3,5-dicarboxylates as potential anticonvulsants and their molecular properties prediction

Published:2013-08 Issue: Volume:66 Page:516-525
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Prasanthi G.,Prasad K.V.S.R.G.,Bharathi K.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference31 articles.

1. Structure–activity relationship of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1);Roh;Bioorg. Med. Chem.,2008

2. Amlodipine enhances the activity of antiepileptic drugs against pentylenetetrazole-induced seizures;Kaminski;Pharmacol. Biochem. Behav.,2001

3. Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproicacid and its tetramethylcyclopropyl analogue;Shekh-Ahmed;Epilepsy Res.,2012

4. Benzofurazinyl- and benzofuroxanyl-1,4-dihydropyridines: synthesis and calcium entry blocker activity;Gasco;Eur. J. Med. Chem.,1996

5. Antihypertensive activity of isradipine in humans: anew dihydropyridine calcium channel antagonist;Nelson;Clin. Pharmacol. Ther.,1986

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