Revisiting ageless antiques; synthesis, biological evaluation, docking simulation and mechanistic insights of 1,4-Dihydropyridines as anticancer agents

Author:

Sidhom Peter A.,El-Bastawissy Eman,Salama Abeer A.,El-Moselhy Tarek F.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference68 articles.

1. CondensationsprodukteausAldehydammoniak und ketonartigenVerbindungen;Hantzsch;Berichte der deutschenchemischen Gesellschaft,1881

2. Recent advances in the chemistry of dihydropyridines;Stout;Chemical reviews,1982

3. Hantzsch's pyridine synthesis;Phillips;Journal of the American Chemical Society,1949

4. Grün, G.; Fleckenstein, A., Electromechanical uncoupling of vascular smooth muscle as the basic principle of coronary dilatation by 4-(2'-nitrophenyl-2, 6-dimethyl-1, 4-dihydropyridine-3, 5-dicarboxylic acid dimethyl ester (BAY a 1040, Nifedipine). 1. The significance of Ca++ ions for the bioelectrical and mechanical activity of smooth muscle. Arzneimittel-Forschung1972,22 (2), 334.

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