Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue

Author:

Shekh-Ahmad Tawfeeq,Bialer Meir,Yavin Eylon

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology

Reference30 articles.

1. Distribution of probenecid-sensitive anion transport processes at the brain capillary endotheium and choroid plexus to the efficient efflux of valproic acid from the central nervous system;Adkison;J. Pharmacol. Exp. Ther.,1994

2. Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI);Bialer;Epilepsy Res.,2002

3. Correlation analysis between anticonvulsant-ED50 values of antiepileptic drugs in mice and rats and their therapeutic doses and plasma levels;Bialer;Epilepsy Behav.,2004

4. Valproic acid: second generation;Bialer;Neurotherapeutics,2007

5. Key factors in the discovery and development of new antiepileptic drugs (AEDs);Bialer;Nat. Rev. Drug Discov.,2010

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