Design, synthesis, biological evaluation, homology modeling and docking studies of ( E )-3-(benzo[ d ][1,3]dioxol-5-ylmethylene) pyrrolidin-2-one derivatives as potent anticonvulsant agents-Reference-Cited by-同舟云学术

Design, synthesis, biological evaluation, homology modeling and docking studies of ( E )-3-(benzo[ d ][1,3]dioxol-5-ylmethylene) pyrrolidin-2-one derivatives as potent anticonvulsant agents

Published:2018-05 Issue:8 Volume:28 Page:1324-1329
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Wang Tiantian,Dong Shiyang,Chen Xiaodong,Qian Kun,Wang Huayu,Quan Hexiu,Zhang Zhongli,Zuo Yueming,Huang Liping,Li Dongxun,Yang Ming,Yang Shilin,Jin Yi,Wang Zengtao

Funder

Jiangxi Provincial Natural Science Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue

2. Molecular targets for the rational design of antiepileptic drugs and related neuroprotective agents

3. Idiosyncratic Adverse Reactions to Antiepileptic Drugs

4. An Animal Model to Study the Clinical Significance of Interictal Spiking

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4. Computational and Synthetic Target-based Approaches to the Discovery of Novel Anticonvulsant Compounds;Current Medicinal Chemistry;2021-10-25

5. Recent advancement in the discovery and development of anti-epileptic biomolecules: An insight into structure activity relationship and Docking;European Journal of Pharmaceutical Sciences;2020-10