Piperidylthiosemicarbazones Cu(II) complexes with a high anticancer activity by catalyzing hydrogen peroxide to degrade DNA and promote apoptosis-Reference-Cited by-同舟云学术

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Piperidylthiosemicarbazones Cu(II) complexes with a high anticancer activity by catalyzing hydrogen peroxide to degrade DNA and promote apoptosis

Published:2018-10 Issue: Volume:158 Page:853-862
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Qi Jinxu,Yao Qian,Tian Liang,Wang Yihong^ORCID

Funder

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Fundamental Research Funds for the Central Universities and Postgraduate Research& Practice Innovation Program of Jiangsu Province

Scientific Research Foundation of Graduated School of Southeast University

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference49 articles.

1. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

2. Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity

3. Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer

4. Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes

5. Advances in Copper Complexes as Anticancer Agents

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1. Synthesis and cytotoxicity of copper(II) semicarbazone complexes with lipophilic counter-anions;Inorganica Chimica Acta;2024-09

2. Recent progress in thiocarbazone metal complexes for cancer therapy via mitochondrial signalling pathway;Frontiers in Chemistry;2024-05-30

3. Synthesis, characterization, biological potency, and molecular docking of Co2+, Ni2+ and Cu2+ complexes of a benzoyl isothiocyanate based ligand;Scientific Reports;2024-05-01

4. ЕЛЕКТРОХІМІЧНИЙ CИНТЕЗ ТА СПЕКТРОФОТОМЕТРИЧНЕ ВИЗНАЧЕННЯ МАЛЕЇНАТНИХ КОМПЛЕКСІВ Cu+;Journal of Chemistry and Technologies;2024-04-26

5. Recently Reported Biological Activities and Action Targets of Pt(II)- and Cu(II)-Based Complexes;Molecules;2024-02-29

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