Discovery of benzofuran-3(2 H )-one derivatives as novel DRAK2 inhibitors that protect islet β-cells from apoptosis-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Discovery of benzofuran-3(2 H )-one derivatives as novel DRAK2 inhibitors that protect islet β-cells from apoptosis

Published:2017-04 Issue: Volume:130 Page:195-208
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Wang Sheng,Xu Lei,Lu Yu-Ting,Liu Yu-Fei,Han Bing,Liu Ting,Tang Jie,Li Jia,Wu Jiangping,Li Jing-Ya,Yu Li-Fang,Yang Fan

Funder

National Key Technology R&D Program

Science and Technology Commission of Shanghai Municipality

Chinese Academy of Sciences

Shanghai Science and Technology Council

Juvenile Diabetes Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference36 articles.

1. The DAPK family: a structure-function analysis;Shiloh;Apoptosis,2014

2. The DAP kinase family of pro-apoptotic proteins: novel players in the apoptotic game;Kogel;BioEssays,2001

3. Transgenic drak2 overexpression in mice leads to increased T cell apoptosis and compromised memory T cell development;Mao;J. Bio. Chem.,2006

4. Drak2 is upstream of p70S6 kinase: its implication in cytokine-induced islet apoptosis, diabetes, and islet transplantation;Mao;J. Immunol.,2009

5. Drak2 overexpression results in increased beta-cell apoptosis after free fatty acid stimulation;Mao;J. Cell. Biochem.,2008

Cited by 39 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Proline-based Organocatalyst for the Synthesis of Arylidene Benzofuranone Intermediates Enabling the Construction of Aurone-derived Azadienes;Current Organic Chemistry;2024-08-22

2. Synthesis of 2‐phenylnaphthalenoid amide derivatives and their topoisomerase IIα inhibitory and antiproliferative activities;Archiv der Pharmazie;2024-06-23

3. Structurally diverse terpenoids and their DRAK2 inhibitory activities: A follow-up study on the vulnerable conifer Pseudotsuga forrestii;Journal of Molecular Structure;2024-06

4. DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser ⁵⁶ to diminish pancreatic β cell function upon overnutrition;Science Translational Medicine;2024-02-07

5. Discovery of aurones bearing two amine functionalities as SHIP2 inhibitors with insulin-sensitizing effect in rat myotubes;RSC Medicinal Chemistry;2024

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3