Structure–activity relationship studies on 1-(2-oxopropyl)indole-5-carboxylic acids acting as inhibitors of cytosolic phospholipase A2α: Effect of substituents at the indole 3-position on activity, solubility, and metabolic stability-Reference-Cited by-同舟云学术

Structure–activity relationship studies on 1-(2-oxopropyl)indole-5-carboxylic acids acting as inhibitors of cytosolic phospholipase A2α: Effect of substituents at the indole 3-position on activity, solubility, and metabolic stability

Published:2017-01 Issue: Volume:125 Page:1107-1114
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Arnsmann Martina,Hanekamp Walburga,Elfringhoff Alwine Schulze,Lehr Matthias

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference18 articles.

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3. Phospholipase A2 inhibitors for the treatment of inflammatory diseases: a patent review (2010-present);Magrioti;Exp. Opin. Ther. Pat.,2013

4. Pyrrolidine inhibitors of human cytosolic phospholipase A2;Seno;J. Med. Chem.,2000

5. Discovery of Ecopladib, an indole inhibitor of cytosolic phospholipase A2α;Lee;J. Med. Chem.,2007

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