Design, synthesis and 3D-QSAR studies of novel 1,4-dihydropyridines as TGFβ/Smad inhibitors-Reference-Cited by-同舟云学术

Design, synthesis and 3D-QSAR studies of novel 1,4-dihydropyridines as TGFβ/Smad inhibitors

Published:2015-05 Issue: Volume:95 Page:249-266
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Längle Daniel,Marquardt Viktoria,Heider Elena,Vigante Brigita,Duburs Gunars,Luntena Iveta,Flötgen Dirk,Golz Christopher,Strohmann Carsten,Koch Oliver,Schade Dennis^ORCID

Funder

Bundesministerium für Bildung und Forschung

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference21 articles.

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2. TGFbeta family signaling: novel insights in development and disease;Wharton;Development,2009

3. Development of TGF-beta signalling inhibitors for cancer therapy;Yingling;Nat. Rev. Drug Discov.,2004

4. Targeting the transforming growth factor-beta signaling pathway in human cancer;Nagaraj;Expert Opin. Investig. Drugs,2010

5. Strategies for TGF-beta modulation: a review of recent patents;Bonafoux;Expert Opin. Ther. Pat.,2009

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2. Expanding the Chemical Space of Transforming Growth Factor-β (TGFβ) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives;ACS Pharmacology & Translational Science;2024-03-21

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4. Synthesis, characterization, crystal structure and Hirshfeld surface analysis of a hexahydroquinoline derivative: tert-butyl 4-([1,1′-biphenyl]-4-yl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate;Acta Crystallographica Section E Crystallographic Communications;2022-07-14

5. Chiral Phosphoric Acid Catalyzed Enantioselective Desymmetrization of 1,4‐Dihydropyridines by C(sp ³ )−H Bromination;Angewandte Chemie International Edition;2022-03-31