Fragments: past, present and future
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Molecular Medicine
Reference48 articles.
1. From fragment to clinical candidate – a historical perspective;Chessari;Drug Discov. Today,2009
2. Drugging challenging targets using fragment-based approaches;Coyne;Curr. Opin. Chem. Biol.,2010
3. Transforming fragments into candidates: small becomes big in medicinal chemistry;de Kloe;Drug Discov. Today,2009
4. A decade of fragment-based drug design: strategic advances and lessons learned;Hadjuk;Nat. Rev. Drug Discov.,2007
5. The multiple roles of computational chemistry in fragment-based drug design;Law;J. Comput. Aided Mol. Des.,2009
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1. Polypharmacology in Drug Design and Discovery—Basis for Rational Design of Multitarget Drugs;Polypharmacology;2022
2. Perspectives on Fragment-based Drug Discovery: A Strategy Applicable to Diverse Targets;Current Topics in Medicinal Chemistry;2021-09-23
3. Divergent Metal-Free [4 + 2] Cascade Reaction of 1-Indanylidenemalononitrile with 3-Benzylidenebenzofuran-2(3H)-one: Access to Spiro-dihydrofluorene-benzofuranone and Axially Chiral Fluorenylamine-phenol Derivatives;Organic Letters;2021-07-09
4. Application of Fragment-Based Drug Discovery to Versatile Targets;Frontiers in Molecular Biosciences;2020-08-05
5. Fragment-based drug design of nature-inspired compounds;Physical Sciences Reviews;2019-06-07
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