Transforming fragments into candidates: small becomes big in medicinal chemistry

Author:

de Kloe Gerdien E.,Bailey David,Leurs Rob,de Esch Iwan J.P.

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference86 articles.

1. The end of the beginning for genomic medicine;Bailey;Nature Biotechnology,2001

2. Structure-based screening and design in drug discovery;van Dongen;Drug Discovery Today,2002

3. Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase;Congreve;Journal of Medicinal Chemistry,2007

4. Fragment-based lead discovery: a chemical update;Erlanson;Current Opinion in Biotechnology,2006

5. Fragment-based drug discovery;Erlanson;Journal of Medicinal Chemistry,2004

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