Anticancer and antibacterial potential of robust Ruthenium(II) arene complexes regulated by choice of α-diimine and halide ligands

Author:

Zanda Emanuele,Busto Natalia,Biancalana Lorenzo,Zacchini Stefano,Biver Tarita,Garcia Begoña,Marchetti Fabio

Funder

Centro de la Fundacio Caixa Castello

Gobierno de Espana Ministerio de Educación Cultura y Deporte

University of Pisa

Junta de Castilla y Leon Consejeria de Educacion

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference95 articles.

1. NAMI-A = (ImidazoleH)[trans-RuCl4(κS-DMSO)(κN-Imidazole)]; KP1019 = (IndazoleH)[trans-RuCl4(κN-Indazole)2]); (N)KP1339/IT-139 = Na[trans-RuCl4(κN-Indazole)2]; TLD1433 = (4,4′-dimethyl-2,2′-bipyridine)(α-terthienyl imidazo[4,5-f][1,10]-phenanthroline)ruthenium(II) dichloride.

2. Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy, Invest;Leijen;New Drugs,2015

3. Safety and activity of IT-139, ruthenium-based compound, in patients with advanced solid tumours: a firstin-human, open-label, dose-escalation phase I study with expansion cohort;A Burris;ESMO Open,2016

4. Therapy from a tumor-centered approach: challenges, opportunities, and highlights from the development of TLD1433;Monro;Chem. Rev.,2019

5. NAMI-A and KP1019/1339, two iconic ruthenium anticancer drug candidates face-to-face: a case story in medicinal inorganic chemistry,;Alessio;Molecules,2019

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3