The beneficial effect of cyclohexyl substituent on the <i>in vitro</i> anticancer activity of diiron vinyliminium complexes-Reference-Cited by-同舟云学术

The beneficial effect of cyclohexyl substituent on the in vitro anticancer activity of diiron vinyliminium complexes

Published:2023 Issue:17 Volume:52 Page:5724-5741
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Benetti Sara¹,Dalla Pozza Maria²^ORCID,Biancalana Lorenzo¹^ORCID,Zacchini Stefano³^ORCID,Gasser Gilles²^ORCID,Marchetti Fabio¹^ORCID

Affiliation:

1. University of Pisa, Dipartimento di Chimica e Chimica Industriale, 56124 Pisa, Italy

2. Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health, Paris, France

3. University of Bologna, Dipartimento di Chimica Industriale “Toso Montanari”, 40136 Bologna, Italy

Abstract

The introduction of a cyclohexyl on a robust di-organoiron scaffold enhances the antiproliferative activity against cancer cell lines influencing the mitochondrial metabolism, and provides a strong selectivity with respect to noncancerous cells.

Funder

H2020 European Research Council

Agence Nationale de la Recherche

Università di Pisa

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D3DT00186E

Reference80 articles.

1. Metallodrugs are unique: opportunities and challenges of discovery and development

2. A survey of the mechanisms of action of anticancer transition metal complexes

3. Classification of Metal-Based Drugs according to Their Mechanisms of Action

4. Application of Metal Coordination Chemistry To Explore and Manipulate Cell Biology

5. Cisplatin: The first metal based anticancer drug

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Anticancer potential of ferrocene-containing derivatives: Current and future prospective;Journal of Molecular Structure;2025-01

2. N-Indolyl diiron vinyliminium complexes exhibit antiproliferative effects in cancer cells associated with disruption of mitochondrial homeostasis, ROS scavenging, and antioxidant activity;Chemico-Biological Interactions;2023-11

3. Ligand and Linkage Isomers of Bis(ethylthiocarbamato) Copper Complexes with Cyclic C₆H₈ Backbone Substituents: Synthesis, Characterization, and Antiproliferation Activity;European Journal of Inorganic Chemistry;2023-09-29