Evidence for CYP2D1-mediated primary and secondary O-dealkylation of ethylmorphine and codeine in rat liver microsomes
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference25 articles.
1. Ethylmorphine O-deethylation cosegregates with the debrisoquine genetic metabolic polymorphism;Rane;Clin Pharmacol Ther,1992
2. Characterization of the common genetic defect in humans deficient in debrisoquine metabolism;Gonzalez;Nature,1988
3. Characterization of specific cytochrome P450 enzymes responsible for the metabolism of diazepam in hepatic microsomes of adult male rats;Neville;Biochem Pharmacol,1993
4. Absence of hepatic cytochrome P450bufl causes genetically deficient debrisoquine oxidation in man;Zanger;Biochemistry,1988
5. The P450 superfamily: update listing of all genes and recommended nomenclature for the chromosomal loci;Nebert;DNA,1989
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Intestinal Absorption Study: Challenges and Absorption Enhancement Strategies in Improving Oral Drug Delivery;Pharmaceuticals;2022-08-08
2. CYP2D6 genetic polymorphisms and their relevance for poisoning due to amfetamines, opioid analgesics and antidepressants;Clinical Toxicology;2015-05-22
3. First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo;Biochemical Pharmacology;2013-06
4. SEX DIFFERENCES IN THE PHARMACOKINETICS, OXIDATIVE METABOLISM AND ORAL BIOAVAILABILITY OF OXYCODONE IN THE SPRAGUE-DAWLEY RAT;Clinical and Experimental Pharmacology and Physiology;2008-03
5. Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine;European Journal of Pharmacology;2004-02-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3