Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man
Author:
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi00415a010
Reference36 articles.
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4. Evidence for an enzymatic defect in the 4-hydroxylation of debrisoquine by human liver.
5. Characterization of a common genetic defect of cytochrome P-450 function (debrisoquine-sparteine type polymorphism) — Increased michaelis constant (km) and loss of stereoselectivity of bufuralol 1′-hydroxylation in poor metabolizers
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