Selective inhibition of indoleamine and tryptophan 2,3-dioxygenases: Comparative study on kynurenine pathway in cell lines via LC-MS/MS-based targeted metabolomics
Author:
Funder
Ministero dell’Istruzione, dell’Università e della Ricerca
Ministero dell'Istruzione dell'Universita e della Ricerca
European Commission
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference36 articles.
1. Tryptophan metabolism and gut-brain homeostasis;Roth;IJMS,2021
2. Indoleamine 2,3–dioxygenase 1 (IDO1): an up‐to‐date overview of an eclectic immunoregulatory enzyme;Pallotta;FEBS J.,2022
3. Tryptophan-catabolizing enzymes - party of three;Ball;Front. Immunol.,2014
4. Tryptophan-restriction diets help to maintain l-tryptophan homeostasis in tryptophan 2,3-dioxygenase knockout mice;Maeta;Int J. Tryptophan Res,2013
5. Challenges and opportunities in the discovery of new therapeutics targeting the kynurenine pathway;Dounay;J. Med. Chem.,2015
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