Validated LC–MS (ESI) assay for the simultaneous determination of amitriptyline and its metabolite nortriptyline in rat plasma: Application to a pharmacokinetic comparison-Reference-Cited by-同舟云学术

Validated LC–MS (ESI) assay for the simultaneous determination of amitriptyline and its metabolite nortriptyline in rat plasma: Application to a pharmacokinetic comparison

Published:2010-11 Issue:3 Volume:53 Page:735-739
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Shen Yuan,Zhu Rong-Hua,Li Huan-De,Liu Yan-Wen,Xu Ping

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference14 articles.

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2. Blood–brain barrier penetration and pharmacokinetics of amitriptyline and its metabolites in p-glycoprotein (abcb1ab) knock-out mice and controls;Uhr;J. Psychiatr. Res.,2007

3. Influence of P-glycoprotein inhibition on the distribution of the tricyclic antidepressant nortriptyline over the blood–brain barrier;Ejsing;Hum. Psychopharmacol.,2005

4. A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression;Roberts;Pharmacogenomics J.,2002

5. Ritonavir and dexamethasone induce expression of CYP3A and P-glycoprotein in rats;Perloff;Xenobiotica,2004

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