Biotransformation and brain distribution of the anti-COVID-19 drug molnupiravir and herb-drug pharmacokinetic interactions between the herbal extract Scutellaria formula-NRICM101-Reference-Cited by-同舟云学术

Biotransformation and brain distribution of the anti-COVID-19 drug molnupiravir and herb-drug pharmacokinetic interactions between the herbal extract Scutellaria formula-NRICM101

Published:2023-09 Issue: Volume:234 Page:115499
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Chang Chun-Hao,Peng Wen-Ya,Lee Wan-Hsin,Lin Tung-Yi,Yang Muh-Hwa,Dalley Jeffrey W.,Tsai Tung-Hu

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference26 articles.

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3. Pharmacokinetics of ß-d-N4-Hydroxycytidine, the parent nucleoside of prodrug molnupiravir, in nonplasma compartments of patients with severe acute respiratory syndrome coronavirus 2 Infection;FitzGerald;Clin. Infect. Dis.,2022

4. USFDA, Molnupiravir, Oral Treatment of COVID-19, EUA #000108 (2021).

5. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice;Sheahan;Sci. Transl. Med.,2020

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1. The anti-COVID-19 drug nirmatrelvir crosses the blood‒brain barrier and exhibits herb–drug pharmacokinetic interactions with Scutellaria baicalensis formulations;Heliyon;2024-08

2. A path from synthesis to emergency use authorization of molnupiravir as a COVID-19 therapy;Bioorganic Chemistry;2024-06

3. Effect of Nucleic Acid Analog Administration on Fluctuations in the Albumin-to-Globulin Ratio in Cats with Feline Infectious Peritonitis;Animals;2024-04-28

4. Inhibitory Efficacy of Main Components of Scutellaria baicalensis on the Interaction between Spike Protein of SARS-CoV-2 and Human Angiotensin-Converting Enzyme II;International Journal of Molecular Sciences;2024-03-02

5. The clinical application of traditional Chinese medicine NRICM101 in hospitalized patients with COVID-19;Expert Review of Anti-infective Therapy;2024-02-02