Exploration of liquid and supercritical fluid chromatographic chiral separation and purification of Nutlin-3—A small molecule antagonist of MDM2-Reference-Cited by-同舟云学术

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Exploration of liquid and supercritical fluid chromatographic chiral separation and purification of Nutlin-3—A small molecule antagonist of MDM2

Published:2007-12 Issue:5 Volume:45 Page:720-729
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Wang Zhenyu,Jonca Malgorzata,Lambros Ted,Ferguson Stephen,Goodnow Robert

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference13 articles.

1. Surfing the p53 network

2. The p53–Mdm2 module and the ubiquitin system

3. Decision making by p53: life, death and cancer

4. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

5. Regulation of p53 stability by Mdm2

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