Synthesis of discodermolide intermediates from engineered polyketides
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference44 articles.
1. Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta
2. Gunasekera, S. P.; Pomponi, S. A.; Longley, R. E. U.S. Patent No. US5840750, November 24 1998.
3. Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol,
4. (+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest
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1. Synthesis of C9‐C13 and C15‐C21 Subunits of Discodermolide;Asian Journal of Organic Chemistry;2020-06-30
2. Porifera (Sponges)-5;Encyclopedia of Marine Natural Products;2014-08-07
3. Organismos marinhos como fonte de novos fármacos: histórico & perspectivas;Química Nova;2009
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5. The Structure Activity Relationship of Discodermolide Analogues;Mini-Reviews in Medicinal Chemistry;2008-03-01
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