Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening-Reference-Cited by-同舟云学术

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Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening

Published:2020-01 Issue: Volume:168 Page:220-230
ISSN:0300-9084
Container-title:Biochimie
language:en
Short-container-title:Biochimie

Author:

Charles M. Ramya Chandar,Mahesh Arun,Lin Shu-Yu,Hsieh Hsing-Pang,Dhayalan Arunkumar,Coumar Mohane Selvaraj

Funder

University Grants Commission, Government of India

Department of Biotechnology, Government of India

DST-FIST

UGC-Special Assistant Programme

National Cheng Kung University

Ministry of Education (MOE), Taiwan

Ministry of Science and Technology, Taiwan

Publisher

Elsevier BV

Subject

General Medicine,Biochemistry

Reference54 articles.

1. Protein methyltransferases as a target class for drug discovery;Copeland;Nat. Rev. Drug Discov.,2009

2. Regulation of p53 activity through lysine methylation;Chuikov;Nature,2004

3. Protein lysine methyltransferase G9a acts on non-histone targets;Rathert;Nat. Chem. Biol.,2008

4. The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation;Ding;Cell Metabol.,2013

5. Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader–Willi syndrome;Kim;Nat. Med.,2017

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1. EHMT2-mediated transcriptional reprogramming drives neuroendocrine transformation in non–small cell lung cancer;Proceedings of the National Academy of Sciences;2024-05-30

2. Integration of ligand and structure-based pharmacophore screening for the identification of novel natural leads against Euchromatic histone lysine methyltransferase 2 (EHMT2/G9a);Journal of Biomolecular Structure and Dynamics;2023-05-22

3. Molecular target interactions of quinoline derivatives as anticancer agents: A review;Chemical Biology & Drug Design;2022-12-30

4. Recent contributions of quinolines to antimalarial and anticancer drug discovery research;European Journal of Medicinal Chemistry;2021-12

5. EHMT2/G9a as an Epigenetic Target in Pediatric and Adult Brain Tumors;International Journal of Molecular Sciences;2021-10-19

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