Integration of ligand and structure-based pharmacophore screening for the identification of novel natural leads against Euchromatic histone lysine methyltransferase 2 (EHMT2/G9a)-Reference-Cited by-同舟云学术

Integration of ligand and structure-based pharmacophore screening for the identification of novel natural leads against Euchromatic histone lysine methyltransferase 2 (EHMT2/G9a)

Published:2023-05-22 Issue: Volume: Page:1-28
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Jana Abhisek¹,Naga Rahul²,Saha Sougata²,Griñán-Ferré Christian³⁴^ORCID,Banerjee Deb Ranjan¹^ORCID

Affiliation:

1. Department of Chemistry, National Institute of Technology Durgapur, Durgapur, India

2. Department of Biotechnology, National Institute of Technology Durgapur, Durgapur, India

3. Department of Pharmacology and Therapeutic Chemistry, Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain

4. Centro de Investigación en Red, Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain

Funder

CRG

SIRE

DST-SERB

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2213346

Reference104 articles.

1. Identification of Potent Caspase-3 Inhibitors for Treatment of Multi- Neurodegenerative Diseases Using Pharmacophore Modeling and Docking Approaches

2. A Combination of Receptor-Based Pharmacophore Modeling & QM Techniques for Identification of Human Chymase Inhibitors

3. Epigenetic protein families: a new frontier for drug discovery

4. Computer Aided Drug Design: Success and Limitations

5. Banerjee, D. R., Deckard, C. E., Zeng, Y. iii, & Sczepanski, J. T. (2019). Acetylation of the histone H3 tail domain regulates base excision repair on higher-order chromatin structures.Scientific Report, 9, 15972 https://doi.org/10.1038/s41598-019-52340-0