Protein methyltransferases as a target class for drug discovery
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2974.pdf
Reference80 articles.
1. Strahl, B. D. & Allis, C. D. The language of covalent histone modifications. Nature 403, 41–45 (2000).
2. Kouzarides, T. Chromatin modifications and their function. Cell 128, 693–705 (2007). A thorough overview of post-translational modifications on core histones, the enzymes that mediate these modifications and the biological functions of the modification.
3. Smith, B. C. & Denu, J. M. Chemical mechanisms of histone lysine and arginine modifications. Biochim. Biophys. Acta 1789, 45–57 (2008). An excellent review of the chemical biology of lysine- and arginine-modifying enzymes.
4. Cole, P. A. Chemical probes for histone-modifying enzymes. Nature Chem. Biol. 4, 590–597 (2008).
5. Keppler, B. R. & Archer, T. K. Chromatin-modifying enzymes as therapeutic targets — Part 1. Expert Opin. Ther. Targets. 12, 1301–1312 (2008).
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