Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening-Reference-Cited by-同舟云学术

Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening

Published:2022-07 Issue: Volume:203 Page:105344
ISSN:0166-3542
Container-title:Antiviral Research
language:en
Short-container-title:Antiviral Research

Author:

Roy Anu,Alhammad Yousef M.^ORCID,McDonald Peter,Johnson David K.,Zhuo Junlin,Wazir Sarah,Ferraris Dana,Lehtiö Lari,Leung Anthony K.L.,Fehr Anthony R.^ORCID

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference45 articles.

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2. Both ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain affect neurovirulence in mice;Abraham;mBio,2020

3. The viral macrodomain counters host antiviral ADP-ribosylation;Alhammad;Viruses,2020

4. The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase;Alhammad;J. Virol.,2021

5. Poly(ADP-Ribose) polymerases in host-pathogen interactions, inflammation, and immunity;Brady;Microbiol. Mol. Biol. Rev.,2019

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1. Extensive exploration of structure activity relationships for the SARS-CoV-2 macrodomain from shape-based fragment merging and active learning;2024-08-26

2. HTRF-based assay for detection of mono-ADP-ribosyl hydrolyzing macrodomains and inhibitor screening;iScience;2024-07

3. PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation;The EMBO Journal;2024-06-04

4. Structural and functional analyses of SARS-CoV-2 Nsp3 and its specific interactions with the 5’ UTR of the viral genome;2024-05-09

5. Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target;Journal of Medicinal Chemistry;2024-04-09