Clarifying intrinsic efficacy, partial agonism, and full agonism: moving beyond efficacy and affinity towards ligand-directed signalling. Comment on Br J Anaesth 2024; 132: 431

登录注册会员服务联系我们

Clarifying intrinsic efficacy, partial agonism, and full agonism: moving beyond efficacy and affinity towards ligand-directed signalling. Comment on Br J Anaesth 2024; 132: 431–2

Published:2024-06 Issue:6 Volume:132 Page:1332-1333
ISSN:0007-0912
Container-title:British Journal of Anaesthesia
language:en
Short-container-title:British Journal of Anaesthesia

Author:

Garland Huw^ORCID

Funder

NIHR

Publisher

Elsevier BV

Reference14 articles.

1. Clarifying intrinsic efficacy, partial agonism, and full agonism: the case of buprenorphine;Samways;Br J Anaesth,2024

2. A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer;Blattermann;Nat Chem Biol,2012

3. Therapeutic potential of beta-arrestin- and G protein-biased agonists;Whalen;Trends Mol Med,2011

4. Biased signalling: from simple switches to allosteric microprocessors;Smith;Nat Rev Drug Discov,2018

5. Pharmacological characters of oliceridine, a mu-opioid receptor G-protein-biased ligand in mice;Liang;Anesth Analg,2019

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP