Leucine-rich repeat 2 of human Toll-like receptor 4 contains the binding site for inhibitory monoclonal antibodies-Reference-Cited by-同舟云学术

Leucine-rich repeat 2 of human Toll-like receptor 4 contains the binding site for inhibitory monoclonal antibodies

Published:2015-11-19 Issue:24PartB Volume:589 Page:3893-3898
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:

Author:

Tsukamoto Hiroki,Ukai Ippo,Yamagata Yuki,Takeuchi Shino,Kubota Kanae,Kozakai Sao,Suzuki Naoto,Kimoto Masao,Tomioka Yoshihisa

Funder

JSPS

Ichiro Kanehara Foundation

Research Foundation for Pharmaceutical Sciences

Tokyo Biochemical Research Foundation

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1016/j.febslet.2015.11.018/fullpdf

Reference23 articles.

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2. Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells;Tsukamoto;Int. Immunol.,2010

3. Reduced surface expression of TLR4 by a V254I point mutation accounts for the low lipopolysaccharide responder phenotype of BALB/c B cells;Tsukamoto;J. Immunol.,2013

4. Inhibition of antibody production in vivo by pre-stimulation of Toll-like receptor 4 before antigen priming is caused by defective B-cell priming and not impairment in antigen presentation;Rachmawati;Int. Immunol.,2013

5. Multiple potential regulatory sites of TLR4 activation induced by LPS as revealed by novel inhibitory human TLR4 mAbs;Tsukamoto;Int. Immunol.,2012

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