Targeted protein degradation: A promise for undruggable proteins
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry
Reference182 articles.
1. PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase;Adhikari;Nat. Chem. Biol.,2020
2. Clonal evolution leading to ibrutinib resistance in chronic lymphocytic leukemia;Ahn;Blood,2017
3. Mutant-selective degradation by BRAF-targeting PROTACs;Alabi;bioRxiv,2020
4. Developing potent PROTACs tools for selective degradation of HDAC6 protein;An;Protein Cell,2019
5. AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer;Antonarakis;N. Engl. J. Med.,2014
Cited by 143 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Targeting Thyroid-Stimulating Hormone Receptor: A Perspective on Small-Molecule Modulators and Their Therapeutic Potential;Journal of Medicinal Chemistry;2024-09-13
2. LYMTACs: Chimeric Small Molecules Repurpose Lysosomal Membrane Proteins for Target Protein Relocalization and Degradation;2024-09-10
3. Exploring Degradation of Intrinsically Disordered Protein Yes-Associated Protein Induced by Proteolysis TArgeting Chimeras;Journal of Medicinal Chemistry;2024-08-27
4. VIPER-TACs leverage viral E3 ligases for disease-specific targeted protein degradation;2024-08-16
5. Targeted Degradation of Protein Kinase A via a Stapled Peptide PROTAC;ACS Chemical Biology;2024-08-13
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3