Author:
Guindon Yvan,Bernstein Michael A,Anderson Paul C
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference19 articles.
1. Dimethylboron bromide and diphenylboron bromide. Acetal and ketal cleavage. Cleavage of MEM, MOM, and MTM ethers.
2. Deoxygenation of sulfoxides with boron bromide reagents
3. Dimethylboron bromide--interconversion of protecting groups: preparation of MTM [(methylthio)methyl] ethers, O,S-acetals, and cyanomethyl ethers
4. This solution could be warmed to room temperature and α-bromo ether 2 could be isolated by evaporation of the excess Me2BBr and postulated byproduct (Me2BOEt). Some hydrolysis of 2 to the corresponding aldehyde occurred, but no significant change in the NMR spectrum of 2 was seen.
5. The intermediacy of an α-bromo ether In the reaction of Me2BBr with an acetal had reviously been inferred on the basis of trapping experiments.
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