Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer-Reference-Cited by-同舟云学术

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Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

Published:2019-11 Issue:5 Volume:36 Page:545-558.e7
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Quereda Victor,Bayle Simon,Vena Francesca,Frydman Sylvia M.,Monastyrskyi Andrii,Roush William R.,Duckett Derek R.

Funder

Rendina Family Foundation

Moffitt Cancer Center and Research Institute

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference51 articles.

1. Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity;Bajrami;Cancer Res.,2014

2. Phosphorylation of RNAPII: to P-TEFb or not to P-TEFb?;Bartkowiak;Transcription,2011

3. ATM, ATR, and DNA-PK: the trinity at the heart of the DNA damage response;Blackford;Mol. Cell,2017

4. The cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes;Blazek;Genes Dev.,2011

5. The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance;Bouwman;Nat. Rev. Cancer,2012

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2. Antitumoral activity of a CDK12 inhibitor in colorectal cancer through a liposomal formulation;Biomedicine & Pharmacotherapy;2024-09

3. Targeting cyclin-dependent kinases: From pocket specificity to drug selectivity;European Journal of Medicinal Chemistry;2024-09

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5. Dual-site molecular glues for enhancing protein-protein interactions of the CDK12-DDB1 complex;Nature Communications;2024-08-01

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