Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity-Reference-Cited by-同舟云学术

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Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity

Published:2013-11-15 Issue:1 Volume:74 Page:287-297
ISSN:0008-5472
Container-title:Cancer Research
language:en
Short-container-title:Cancer Res

Author:

Bajrami Ilirjana,Frankum Jessica R.,Konde Asha,Miller Rowan E.,Rehman Farah L.,Brough Rachel,Campbell James,Sims David,Rafiq Rumana,Hooper Sean,Chen Lina,Kozarewa Iwanka,Assiotis Ioannis,Fenwick Kerry,Natrajan Rachael,Lord Christopher J.,Ashworth Alan

Publisher

American Association for Cancer Research (AACR)

Subject

Cancer Research,Oncology

Cited by 297 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An update on small molecule compounds targeting synthetic lethality for cancer therapy;European Journal of Medicinal Chemistry;2024-11

2. PARP inhibitor resistance mechanisms and PARP inhibitor derived imaging probes;Expert Review of Anticancer Therapy;2024-09-03

3. CDK12 is a promising therapeutic target for the transcription cycle and DNA damage response in metastatic osteosarcoma;Carcinogenesis;2024-07-31

4. Tracking down metabolic vulnerabilities in CDK12‐mutant prostate cancer;Clinical and Translational Discovery;2024-07-19

5. Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies;2024-07-19

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