Dual-site molecular glues for enhancing protein-protein interactions of the CDK12-DDB1 complex-Reference-Cited by-同舟云学术

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Dual-site molecular glues for enhancing protein-protein interactions of the CDK12-DDB1 complex

Published:2024-08-01 Issue:1 Volume:15 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Zhang Zemin^ORCID,Li Yuanqing,Yang Jie,Li Jiacheng,Lin Xiongqiang,Liu Ting,Yang Shiling,Lin Jin,Xue Shengyu,Yu Jiamin,Tang Cailing,Li Ziteng^ORCID,Liu Liping,Ye Zhengzheng,Deng Yanan^ORCID,Li Zhihai,Chen Kaixian,Ding Hong,Luo Cheng^ORCID,Lin Hua^ORCID

Funder

National Natural Science Foundation of China

Natural Science Foundation of Fujian Province

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41467-024-50642-0.pdf

Reference49 articles.

1. Zhang, Q. C. et al. Structure-based prediction of protein–protein interactions on a genome-wide scale. Nature 490, 556–560 (2012).

2. Kim, M. et al. A protein interaction landscape of breast cancer. Science 374, eabf3066 (2021).

3. Garlick, J. M. & Mapp, A. K. Selective modulation of dynamic protein complexes. Cell Chem. Biol. 27, 986–997 (2020).

4. Dewey, J. A. et al. Molecular glue discovery: current and future approaches. J. Med. Chem. 66, 9278–9296 (2023).

5. Xue, Y., Bolinger, A. A. & Zhou, J. Novel approaches to targeted protein degradation technologies in drug discovery. Expert Opin. Drug Discov. 18, 467–483 (2023).

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