Molecular modelling of human microsomal epoxide hydrolase (EH) by homology with a fungal (Aspergillus niger) EH crystal structure of 1.8 Å resolution: structure–activity relationships in epoxides inhibiting EH activity-Reference-Cited by-同舟云学术

Molecular modelling of human microsomal epoxide hydrolase (EH) by homology with a fungal (Aspergillus niger) EH crystal structure of 1.8 Å resolution: structure–activity relationships in epoxides inhibiting EH activity

Published:2005-06 Issue:4 Volume:19 Page:517-522
ISSN:0887-2333
Container-title:Toxicology in Vitro
language:en
Short-container-title:Toxicology in Vitro

Author:

Lewis David F.V.,Lake Brian G.,Bird Michael G.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference18 articles.

1. Mammalian xenobiotic epoxide hydrolases;Arand,2002

2. Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase;Arand;Biochemical Journal,1999

3. Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate;Arand;Biochemical Journal,1999

4. Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation;Argiriadi;Journal of Biological Chemistry,2000

5. Detoxification of environmental mutagens and carcinogens: structure, mechanism and evolution of liver epoxide hydrolase;Argiriadi;Proceedings of the National Academy of Sciences, USA,1999

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