An integrated testing strategy for in vitro skin corrosion and irritation assessment using SkinEthic™ Reconstructed Human Epidermis

Author:

Alépée Nathalie,Grandidier Marie-Hélène,Tornier Carine,Cotovio José

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference20 articles.

1. A catch-up validation study on reconstructed human epidermis (SkinEthicTM RHE) for full replacement of the Draize skin irritation test;Alépée;Toxicol. in Vitro,2010

2. The usefulness of the validated SkinEthic™ RHE test method to identify skin corrosive UN GHS subcategories;Alépée;Toxicol. In Vitro,2014

3. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes;Draize;J. Pharm. Exp. Ther.,1944

4. EC, 2008. REGULATION (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. Official Journal of the European Union L353, 1-1355.

5. ESAC, 2006. Statement on the application of the SkinEthicTM human skin model for skin corrosivity testing, issued by the ECVAM Scientific Advisory Committee (ESAC25), 17 November 2006. .

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