The usefulness of the validated SkinEthic™ RHE test method to identify skin corrosive UN GHS subcategories

Author:

Alépée Nathalie,Robert Clément,Tornier Carine,Cotovio José

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference22 articles.

1. A catch-up validation study on reconstructed human epidermis (SkinEthic™ RHE) for full replacement of the Draize skin irritation test;Alépée;Toxicol. In Vitro,2010

2. EC, 2001. Commission Directive 2001/59/EC of 6 August 2001 adapting to technical progress for the 28th time Council Directive 67/548/EEC on the approximation of laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances. Official Journal of the European Union L225, 1–333.

3. EC, 2006. REGULATION (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No. 793/93 and Commission Regulation (EC) No. 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. Official Journal of the European Union, 2006, L 396,1.

4. EC, 2008. REGULATION (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No. 1907/2006. Official Journal of the European Union L353, 1–1355.

5. ESAC, 2006. Statement on the application of the SkinEthic™ human skin model for skin corrosivity testing, issued by the ECVAM Scientific Advisory Committee (ESAC25), 17 November 2006. . (accessed 15.07.13).

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