Synthesis and biological activity of a squalenoid maleimide and other classes of squalene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference39 articles.
1. The Folding of Squalene; An Old Problem has New Results
2. The squalene-2,3-epoxide cyclase as a model for the development of new drugs
3. Physiology and Biochemistry of Sterols;Cattel,1992
4. Regulation of Isopentenoid Metabolism;Cattel,1992
5. 2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analog inhibitor of 2,3-oxidosqualene cyclase
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3. Versatile and Efficient Synthesis of ω-Functionalized Asymmetric Disulfides via Sulfenyl Bromide Adducts;Langmuir;2007-01-24
4. Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase;Bioorganic & Medicinal Chemistry Letters;2007-01
5. Access of the Substrate to the Active Site of Yeast Oxidosqualene Cyclase: An Inhibition and Site-Directed Mutagenesis Approach;ChemBioChem;2005-10-19
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