Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase-Reference-Cited by-同舟云学术

Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase

Published:2007-01 Issue:1 Volume:17 Page:220-224
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Galli Ubaldina,Oliaro-Bosso Simonetta,Taramino Silvia,Venegoni Serena,Pastore Emanuele,Tron Gian Cesare,Balliano Gianni,Viola Franca,Sorba Giovanni

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

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2. Lord of the rings – the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear

3. The biosynthesis of steroids and triterpenoids

4. Abe, I.; Prestwich, G. D. Comprehensive Natural Products Chemistry. Isoprenoids Including Carotenoids and Steroids; Cane, D., Ed.; Elsevier: Oxford, 1999; Vol. 2, pp 267–298.

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